Identification and tracking technology of the hott

Identification and tracking technology of pharmaceutical packaging

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core tip: the sale of dangerous drugs worldwide has been placed on the agenda of law and regulation makers, who will formulate very strict relevant regulations to prevent product plagiarism. At the same time, different countries also have many different traceability provisions. For example, the United States has regulations on the electronic Genealogy (tracking monitoring) technology of drugs such as e-pedigree, Italy has bollino, Turkey has IST (ILAC takip Sistemi), and so on. Within the EU, there is a famous 2011/62/eu technical specification under the name of the technical specification for drug production. This technical specification requires that from 2017, prescription drug packages sold in all EU countries should bear anti-counterfeiting labels and serial numbers

[China Packaging News] it has been put on the agenda of law and regulation makers to sell dangerous drugs worldwide. They will formulate very strict relevant regulations to prevent product plagiarism. At the same time, different countries also have many different traceability provisions. For example, the United States has regulations on the electronic Genealogy (tracking monitoring) technology of drugs such as e-pedigree, Italy has bollino, Turkey has IST (ILAC takip Sistemi), and so on. Within the EU, there is a famous 2011/62/eu technical specification under the name of the technical specification for drug production. This technical specification requires that from 2017, prescription drug packages sold in all EU countries should bear anti-counterfeiting labels and serial numbers

for drug manufacturing enterprises, this means that they need to pay more auxiliary expenses. The future drug packaging production line must have corresponding infrastructure and the ability to identify and track. Whoever wants to transform the existing pharmaceutical packaging production line and install the corresponding instruments and equipment needs to deal with various interface technologies. A requirement that can be met without complex technology needs to pay a high price, and this is also applicable to the procurement and manufacturing of new packaging lines

5. LED digital display today, Schubert pharma company provides an alternative solution for those pharmaceutical manufacturing enterprises that intend to invest newly, a solution involving Schubert's high compact TLM technology

use traditional technology to realize identification and tracking

all large pharmaceutical manufacturing enterprises have their own identification and tracking technology projects. The premise of this project is the reliable management of various packaging codes in the enterprise level data management system, which is subject to the friction between the bearing surface of bolts and nuts and the friction between screw teeth. Generally speaking, the production plan management system PPS has a connection interface with the production plan layer. The MES manufacturing execution system with vertical structure also connects the drug production process. The serial number to realize serialization is generally generated by PPS production plan management system or directly by the equipment control system of drug packaging production line

how to realize serialization, identification and tracking in the packaging production line according to the conventional method? The smallest product unit, such as the original anti-counterfeiting package that the equipment can achieve, will be broken down into smaller units, and all of them should be marked with a consistency identification number. The camera verifies the correctness of the identification number

when drugs are transported from the conveyor belt to the next production process, for example, when the packaging box is put into the packaging box delivered from the factory, it is necessary to re collect the consistency identification of each drug packaging box in the packaging box, that is, the serial number. When the packaging equipment packs the originally packaged drugs into the packaging box, the camera monitoring system should re monitor and review this process

the information of recognition and tracking is continuously improved in turn. Each single and separately executed production process should have corresponding monitoring equipment, such as cameras and monitoring scales

in this error free equipment and tracking function, the equipment should ensure the coordination of the whole process and the smooth communication between all systems and components. This is also a high requirement for the operation of existing and later added equipment

a glimpse of eyedrops packaging equipment

use the TLM technology of fastening the nuts of the equipment regularly to realize equipment and tracking

tlm Pharma's equipment has the ability to directly intervene in the production process and track data information from the beginning, and it does not provide an island solution. The packaging equipment control system VMS of Schubert company is believed by the industry to include all functions of the final packaging of serialized drugs. Pallet transportation from receiving finished drugs to boxes of drugs. All automation equipment required for serialization, such as robots, scanners, cameras and printers, can establish communication with VMS packaging equipment control system

the delivery module can deliver pharmaceutical products within the whole equipment. Within the whole equipment, it ensures that the drug products will never be in an uncontrolled state during a straight-line movement

this conveying module can be used as a single axis push robot, and its motion position can be determined at any time (100% position monitoring). The products transported by the conveying module can also be 100% monitored. For example, when the robot picks up the serialized packaging box and puts it into the factory packaging box, the monitoring system will receive the drugs of which series number packaging box are put into which series number packaging box. And these information do not need to be collected and sent by the camera system

the advantages of this are:

● information will be integrated into a system in real time, and VMS control system collects data and information in the whole production process

● in the production process, no equipment or instrument uses other control software, and there is no interface problem; All data collected by printers, cameras, etc. are directly saved to the production line management system and VMS control system

● the number of components used in the traceability process is very small, and the cost of certification is very small

● unimpeded communication

● unified operation interface

schubert Pharma uses TLM standard components with matching performance to configure the whole packaging production line, VMS control system, robot, visual monitoring system, electronic technology components and identification and tracking solutions consistent with user requirements. All technologies are independently developed by Schubert company and have been tested for many years

the conveying module can be used as a single axis push robot, and its motion position can be defined at any time (the picture shown in the figure is the picture of the personalized medical product production equipment of Hoffmann Laroche company)

New TLM components ensure higher quality

Schubert company continues to develop new components required for TLM technology. At the Interpack international packaging machinery, packaging and confectionery machinery exhibition, they showed their independently developed 3D scanner. The video detection system can create the front outline of the three-dimensional shape of the product to be packaged. Schubert system provides monitoring of parameters such as volume, weight and stacking height of packing cases. Since the scanner scans the product from two directions and different perspectives (holographic stereo scanning), sufficient redundant information can be obtained, which reduces the scrap rate. For high-cost drugs or efficient production equipment, the investment cost of this system will be recovered soon. The installation and configuration of the image processing system suppresses the reflection, which significantly reduces the error rate in the analysis and evaluation of the detection data

experience from practice

schubert Pharma Company began to adopt the equipment scheme with identification and tracking functions in the packaging production line for the first time in 2005. The first user is Solvay company, and today there is Abbott company in the United States. The operation of product tracking and data maintenance of the packaging line shall be carried out in accordance with the graphic symbols of the Italian (bollini) standard

in many other projects, there are many special data tracking requirements, personalized identifications of different drug manufacturers, and different product and packaging specifications

Hoffmann La Roche will give an answer to the performance level of traceability achieved by TLM technology after acceptance of the packaging equipment put into production. This equipment produces complete sets of drugs and accessories for personalized medical use. The data management of personalized medicine serialization of this packaging equipment is far beyond the scope of identification and tracking

in order to produce each set of drugs and accessories required for personalized medical treatment, it is not enough to only record the inspection records of what products are in which packaging box. The control system of the equipment carries out accurate drug packaging monitoring according to different patients, down to which box is packed and who uses what. This ensures that every patient can finally get the drugs they need

high end interview

Schubert Pharma: rich professional skills in final packaging

in January 2014, Schubert Pharma was officially established. Under the name of this company, there is a technical team composed of 20 experts: a professional company specialized in providing packaging solutions for pharmaceutical industry enterprises under the unified leadership of IPS, a subsidiary of Schubert. Ms. ankegeipel Kern, executive editor of pharma Tec magazine, interviewed Mr. Gerald Schubert, manager of Schubert pharma company, and learned about some users' requirements and ideas for this newly established professional organization

mr. Schubert, what is the reason for the establishment of Schubert Pharma

the establishment of this subsidiary is part of the growth strategy of our head office. We will further develop the world-renowned Schubert brand

why is it a subsidiary relying on IPS

this question is the best answer from a historical perspective. IPS is an engineering design company subordinate to our head office. It has been specialized in equipment manufacturing engineering projects since the 1990s, and has also completed many projects in the pharmaceutical field. It has accumulated rich professional technical knowledge and experience in project management, as well as experience in certification and audit. On this basis, we have established a special organization that can undertake the professional design of very complex pharmaceutical equipment. In this way, we can make use of the professional technical knowledge and experience of Schubert and IPS

pharmaceutical packaging equipment is an excellent representative of special equipment manufacturing in the pharmaceutical field. How flexible is TLM technology with highly standardized modules

it is precisely this transport module that opens up many new possibilities. Through the miniaturization of mechanical structure, the high intelligence of our control system and the principle of changing tooling enable us to use standardized parts to complete special tasks

what is the role of the delivery module in drug packaging

by 2017, all drug packaging equipment should be equipped with a product traceability system. Our conveying module has the performance of robot, which can realize 100% positioning control, that is to say, people can know the exact position of packages all the time. With this function, we can track the packaging materials in the whole packaging process, from filling to labeling to stacking on the pallet, so as to ensure compliance with the requirements and provisions of relevant laws and regulations and technical specifications